Logo tutelle


Sur ce site

Sur le Web du CNRS

Accueil du site > Séminaires, conférences > Séminaires du LIP > Séminaires en 2008 > ULTRASOUND ECHOES FROM TARGETED CONTRAST AGENTS.


Date : 16/05/2008 à 13h30

Intervenants :
- Olivier COUTURE, PhD, Laboratoire Ondes et Acoustique, ESPCI, previously at the Department of Medical Biophysics, University of Toronto.

Résumé :

Targeted contrast agents allow molecular imaging in-vivo by binding to cells expressing molecular biomarkers of disease and enhancing their contrast in ultrasound images. The ultrasound echo from targeted contrast agents is poorly understood because it is not only affected by their acoustical properties, but also by their surface densities and spatial distribution. The goal of my thesis at the University of Toronto was to develop models to predict the contrast enhancement obtainable from different types of targeted agents. The concepts developed were also generalized to the ultrasound reflection of spherical particles forming layers to mimic the echo formation from a complex tissue. Recently, at the Laboratoire Ondes et Acoustique in Paris, we have been applying the concept of targeted contrast agents to ultrasound therapy.