LJP at a glance

LJP research activities consist in Physics at the interface of with Biology and Medicine. We develop new experimental approaches to probe complex biological systems at different scales, and we develop bio-inspired systems to develop new concepts or to improve our understanding of given biological mechanisms. A large part of our research aims at exploring the response of a biological system to external perturbations. Finally, the LJP includes a theoretical component closely interacting with experimenters.

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  Lightsheet fluorescence microscopy

  With this microscopy technique, thin slices of the sample are illuminated perpendicularly to the direction of observation. It enables a high data thoughput and reduces the photodamage and stress induced on a living sample. At Jean Perrin, we combine lightsheet microscopy with calcium imaging to monitor the activity of tens of thousands of neurons in the zebrafish brain.

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  Millifluidics for biology

  Millifluidic devices of molded PDMS allows to impose different channel geometries and thus to fine-tune the system hydrodynamical properties. The preparation is simple, fast and reproducible. At Jean Perrin, we use this technique to study the impact of physical parameters on the development of bacterial biofilms.

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Next seminar

27 SEP

Vitrimers: Insoluble yet reshapable chemically crosslinked networks By François Tournilhac (ESPCI, Lab. Matière molle et chimie) September 27, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Vitrimers, invented in 2011, are chemically crosslinked networks characterized by the presence of exchangeable links, a feature that allows to change topology while keeping the integrity of the ...

News

14
SEP 2017

Publication: Sensorimotor computation underlying phototaxis in zebrafish
Nature Communication in press, , doi:

28
AUG 2017

Publication: Structural changes and picosecond to second dynamics of ...
Physical Chemistry Chemical Physics 19, 32, doi:10.1039/c7cp02634j

05
JUL 2017

Moving
Philippe Thomen leaves the LJP which he joined in June 2012. He will join l'INstitut de PHYsique de NIce ...

28
JUN 2017

Publication: Blind sparse deconvolution for inferring spike trains from ...
BioArxiv , , doi:10.1101/156364

03
MAY 2017

Publication: Synthesis and materialization of a reaction-diffusion French flag...
Nature chem. 1, 1, doi:10.1038/nchem.2770

01
MAY 2017

Programming an aqueous solution to paint a "French flag"
Inspired by a process happening at the beginning of embryonic development, a team of chemists and physicists ...

12
APR 2017

Publication: Bacterial biofilm under flow: First a physical struggle to stay, ...
PLOS ONE 12, 4, doi:10.1371/journal.pone.0175197

29
MAR 2017

Publication: Raman scattering-based multiconformational analysis for probing ...
Journal of Pharmaceutical and Biomedical Analysis 138, , doi:10.1016/j.jpba.2017.01.049

21
FEB 2017

HdR defense of Raphaël Candelier
Raphaël Candelier is delighted to invite you to his habilitation à diriger des recherches defense ...

30
JAN 2017

Publication: Microscopic agents programmed by DNA circuits
Nature Nano 1, 1, doi:10.1038/nnano.2016.299