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Anne-Florence Bitbol anne-florence.bitbol@upmc.fr
CNRS Research Scientist
Office (room 510)
Fax
(+33) 1 44 27 40 29
(+33) 1 44 27 47 16

Research interests

Stochastic dynamics of reactive and living systems

Presentation

I am interested in understanding living organisms and living matter thanks to physics, especially statistical physics, but also thanks to other quantitative approaches. I perform both analytical work and numerical simulations, and I enjoy collaborating with experimentalists. My work spans various scales, from molecules and cells to populations.

For my PhD, at Universite Paris-Diderot, I worked on the statistics and dynamics of complex membranes.

For my postdoc, at Princeton University (USA), I worked on various aspects of the link between functions and constraints in multi-protein complexes.

More details are available on my webpage.


Publications

2020

Resist or perish: Fate of a microbial population subjected to a periodic presence of antimicrobial - PLOS Computational Biology
L. Marrec , A.F. Bitbol
  URL Full text PDF Bibtex doi:10.1371/journal.pcbi.1007798
Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance - Soft Matter
P. Thomen , J.D. Valentin , A.F. Bitbol , N. Henry
  URL Full text PDF Bibtex doi:10.1039/c9sm01375j

2019

Phylogenetic correlations can suffice to infer protein partners from sequences - PLoS Computational Biology
G. Marmier , M. Weigt , A.F. Bitbol
  URL Full text PDF Bibtex doi:10.1371/journal.pcbi.1007179
Revealing evolutionary constraints on proteins through sequence analysis - PLoS Computational Biology
S.W. Wang , A.F. Bitbol , N.S. Wingreen
  URL Full text PDF Bibtex doi:10.1371/journal.pcbi.1007010

2018

Membrane-Mediated Interactions - Physics of Biological Membranes, Bassereau P., Sens P. (eds), Springer, Cham
A.F. Bitbol , D. Constantin , J.B. Fournier
  URL Full text PDF Bibtex doi:10.1007/978-3-030-00630-3_13
Inferring interaction partners from protein sequences using mutual information - PLoS Computational Biology
A.F. Bitbol
  URL Full text PDF Bibtex doi:10.1371/journal.pcbi.1006401
pH sensing by lipids in membranes: The fundamentals of pH-driven migration, polarization and deformations of lipid bilayer assemblies - Biochimica et Biophysica Acta - Biomembranes
M.I. Angelova , A.F. Bitbol , M. Seigneuret , G. Staneva , A. Kodama , Y. Sakuma , T. Kawakatsu , M. Imai , N. Puff
  URL Full text PDF Bibtex doi:10.1016/j.bbamem.2018.02.026

2017

2016

Inferring interaction partners from protein sequences - PNAS
A.F. Bitbol , R.S. Dwyer , L.J. Colwell , N.S. Wingreen
  URL Full text PDF Bibtex doi:10.1073/pnas.1606762113